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What is Morphine?
Opioids are the most powerful medication used to treat pain. Opioid drugs bind to opioid receptors that are present in many areas of the body, including the brain, spinal cord, and gastrointestinal tract. Opioid drugs bind to the receptor, reducing the transmission of pain information to the brain, which reduces pain. Opioids are used to treat moderate to severe pain, and other analgesics do not control this pain well. They don’t treat the root cause of pain. When cancer causes pain, cancer treatment aims to relieve the pain. There are different formulas for morphine. The preparation is a fast-acting medication for the treatment of acute pain. Acute pain refers to pain that occurs quickly and temporarily and is sometimes referred to as breakthrough pain. This medicine can be used with another medicine to treat chronic pain.
How to use Morphine?
Prolonged-release morphine capsules and prolonged-release tablets can only be used by patients who have taken narcotic analgesics (also known as opioids). These patients are called opioid tolerance. If you are not sure whether you can tolerate opioids, please consult your doctor before using the medication. Swallow the entire delayed-release capsule and the delayed-release tablet. Do not crush, crush, dissolve or chew. Do not use damaged parts with extended-release. If you can’t swallow the prolonged-release capsule, you can open it and pour it into a small amount of applesauce. Stir the mixture thoroughly and swallow immediately without chewing. Do not take this medicine through the gastric tube.
The effects of sustained-release morphine capsules or tablets are different from conventional oral morphine liquids or tablets, even if the dose is the same. Don’t switch from one brand or shape to another unless your doctor tells you to.
Side Effects Of Morphine
Morphine and its required effects can cause some adverse effects. Although not all of these side effects can occur, you may need medical attention if they occur. If you have any of the following side effects while taking morphine, please contact your doctor immediately:
- Blurred vision
- Vulnerabilities in the head
- Burning, crawling, itching, numbness, tingling, “acupuncture” or tingling
- Chest pain or discomfort
Precautions Of Morphine
- Elderly, cachexia, or frail patients are more likely to suffer from respiratory depression as their pharmacokinetics or clearance rate may change compared to young, healthy patients.
- Monitor patients with severe chronic obstructive pulmonary disease or pulmonary heart disease, as well as patients with respiratory reserve, hypoxia, hypercapnia, or a significant reduction in existing respiratory depression, especially at the start of treatment. Morphine sulfate prolonged-release tablets are titrated. In these patients, even a conventional therapeutic dose of morphine sulfate can reduce the respiratory drive to apnea.
- Using prolonged-release morphine sulfate tablets in combination with other central nervous system inhibitors (e.g. sedatives, anxiolytics, hypnotics, antipsychotics, muscle relaxants, other opioids) may result in hypotension and severe sedation and coma, or respiratory depression.
- Morphine sulfate can cause severe hypotension in outpatients, including orthostatic hypotension and syncope. Avoid prolonged-release morphine sulfate tablets in patients with cyclical shock.
- The respiratory reserve is significantly reduced in patients with chronic obstructive pulmonary disease or pulmonary heart disease. Patients with hypoxia, hypercapnia, or patients who already have respiratory depression should be particularly careful.
- Morphine is an opioid agonist searched for by drug users and addicted patients and redirected to crime.
- Morphine sulfate can reduce respiratory drive and the resulting CO2 retention further increases brain pressure. Opioids can also make the clinical course of patients with head injuries difficult to understand. Avoid prolonged-release morphine sulfate tablets in conscious or coma patients.
- Patients with gastrointestinal obstruction should avoid the use of prolonged-release morphine sulfate tablets. Morphine sulfate can cause Oddi sphincter spasm. Opioids can cause increased serum amylase.
- Morphine can make convulsions worse in patients with convulsive disorders and can trigger or worsen seizures in certain clinical situations.
- Use mixed opioid agonist and antagonist analgesics in patients who have received or are receiving morphine sulfate as they can cause withdrawal symptoms.
- Morphine sulfate can impair the mental or physical abilities required to carry out potentially dangerous activities (e.g. driving a car or operating a machine).
Storage Of Morphine
Store Morphine at room temperature. Because of the risk of metastasis (someone is taking your anesthesia for greater effectiveness rather than alleviating symptoms), you may need to consider storing the drug in a locker or other safe place.
Drug Interactions Of Morphine
Keep a list of all the products you use (including prescription / over-the-counter and herbal products) and tell your doctor and pharmacist. Do not start, stop, or change the dosage of a drug without the permission of a doctor. Some products that may interact with the drug include certain analgesics (mixed opioid agonists/antagonists such as pentazocine, nalbuphine, and oxprenolol), naltrexone.
Overdose Of Morphine
If morphine overdose is suspected, the following symptoms may occur:
- Blue nails and lips
- Difficulty breathing, shallow breathing, slow and tired breathing, no breathing
- Possible seizures
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